Oral vitamin D tablets
Oral Vitamin D tablets are routinely used for the treatment of vitamin D deficiency. The Endocrine Society recommends the amount of vitamin D to take adults daily to keep their 25 (OH) D-serum levels constant over 30 ng / ml. In several extensive clinical trials, however, it was found that the daily doses are adhered to only a small extent. What is the right dose of vitamin more
Problems in observing the dosage were associated with gastric reflux, with the combination of vitamin D and calcium tablets, with gastrointestinal side effects, with the number of medications that occupies a patient at the same time, and with the attitude of the patient for vitamin D Insert. Vitamin D Has a long half-life, explaining why it has a long-lasting effect on the body. Either Vitamin D In 25 (OH) D converted or fat is absorbed and releases slow vitamin D over time. Ish-Shalom et al. found out that the 25 (OH) D concentrations are equal in the blood, regardless of whether vitamin D is taken daily, weekly or monthly.
In week 12, the 25 (OH) D concentration only reached Ilahi et al., Which is an otherwise vitamin D-poor group 100,000 IE Vitamin D3 administered a value of> 30 ng / ml. The PTH concentrations did not notice noticeably in this study.
Vitamin D3 oil
Only a few studies have examined the potential side effects of a high vitamin D dose. Vitamin D3 in plant oil solution and 200,000 IE vitamin D2 tablets led to vomiting two subjects. In contrast, Rossini et al. In three subjects, there is an increase of numerous bone conversion indicators (connective tissue type 1, pass N-Telopeptide and collagen type 1, pass C-Telopeptide). The results of Rossini et al. However, were statistically not significant. A dose of 300,000 IE Vitamin D3 corrected a severe hypercalcemia (> 10.76 mg / dL) for two participants after six months. There are reports of hypercalzuria, which occurred within 12 weeks after taking 600,000 IE Vitamin D3, as well as an increase in magnesium in the urine three days after taking 600,000 IE vitamin D3. Hypercalciuria cases were not associated with serious health problems. Although calcium and magnesium values were normal in the serum in these individuals, the clinical relevance of increased magnesium in the urine was also not apparent.
Too much vitamin D
A too high vitamin D levels, the so-called hypervitaminosis D, is a rare, but potentially dangerous disease.
High vitamin D cans are the most common cause of vitamin D toxicity, not the diet or sun damage. A vitamin D scarcity can occur even if you take enriched foods as your body itself controls how much vitamin D is formed by sunlight.
Side effect of vitamin D
A side effect of vitamin D deficiency is an accumulation of calcium in blood (hypercalemia), which can lead to nausea, vomiting, fatigue and frequent urination. It can lead to bone complaints and kidney complications, e.g. B. to form calcium stones in the kidney. In the context of the treatment, the inclusion of Vitamin D and calcium are restricted. Your doctor can also recommend intravenous fluid and medicines such as corticosteroids or bisphosphonates.
Vitamin D toxicity was documented after taking 60,000 global units (IU) a day over several months. This vitamin D levels is many times higher than the RDA value of 600 ies a day for most adults in the United States.
Rich in vitamin D
A vitamin D deficiency can be cured with higher doses than the RDA, but only under medical supervision for a certain period of time. A high vitamin D content requires careful monitoring of the blood level.
Before taking vitamin and mineral preparations, consult a doctor.